The Men's African Super Cup 2021, originally supposed to take place in Morocco on 17 May but postponed due to the COVID-19 pandemic, was staged in Cairo, Egypt on 10 September.

RESULT

Zamalek SC vs Al Ahly 28:27

The event served as qualification for the 2021 IHF Men's Super Globe and with their win, Zamalek were determined as final participant of the event.